Folding@home (sometimes abbreviated as FAH or F@h) is a distributed computing (DC) project designed to perform computationally intensive simulations of protein folding and other molecular dynamics (MD). It was launched on October 1, 2000, and is currently managed by the Pande Group, within Stanford University's chemistry department, under the supervision of Professor Vijay Pande. Folding@home is the most powerful distributed computing cluster in the world, according to Guinness[1], and one of the world's largest distributed computing projects.[2] The goal of the project is "to understand protein folding, misfolding, and related diseases."[3]
http://en.wikipedia.org/wiki/Folding@home
so basically "please leave your PS3 on at all times so that it will overheat and break faster."