This is a lose-lose situation. If he stays true to the original, everyone will hate it will have an actual coherent narrative sustained throughout each episode and will lack the non-sequiturs and raunch that made MacFarlane popular. If he does it in the style of his currently successful shows, everyone will hate it because it's not actually the Flintstones.

So either way, it will be panned by fans and critics.

Also, it will probably be awful.

Does anyone remember the Yogi Bear and Jetsons shorts that John K did? They were fucking shameful. Then again, pretty much everything John K did besides the first season or two of Ren & Stimpy was pretty awful.

John K has a lot of respect for the early Looney Tunes/Merrie Melodies stuff, particularly Bob Clampett, and he considered himself to be the logical extension of Bob Clampett's work. I would strongly disagree with John's branding of himself, or at the very least argue that if he's right, that Clampett is lucky to have been restrained by the social moorings of his time.

Clampett did produce a lot of great cartoons in his own right, for which he deserves credit. But he did often try to claim full credit on collaborative ideas such as Bugs Bunny, which made him an outcast among his peers in later life.

I like the Jones later stuff, probably because a lot of it aired on Nickelodeon as "Special Delivery" aka We Don't Have Very Much Original Programming Yet So Here's An Animated Movie And/Or Special. I remember liking Rikki-Tikki-Tavi and A Cricket In Times Square a lot. And his animated sequences in Gremlins 2 and Stay Tuned were both very fun.

Yeah, American Dad is fantastic. My understanding is that's the one Seth works full-time on as a writer.